Research

Berteau Lab conducts the following research:

Line 1 

Bone mineralization and mechanical behavior: from cell's genetics to the risk of fracture

Bone is an engineering marvel. It is a hard-soft hybrid biomaterial that achieves an astonishing combination of stiffness, strength, and toughness which far exceeds that of synthetized materials. Our research focuses on determining the key biological factors that govern bone’s mechanical behavior. This research can be expected to add to our fundamental understanding of how to (i) synthesize hard-soft materials having innovative mechanical properties and (ii) predict the risk of fracture.

Line 2 

Osteoarthritis: from early diagnosis to a better treatment

Osteoarthritis (OA) is the most common type of joint disease starting from a biochemical breakdown of articular cartilage. However, osteoarthritis involves also the subchondral bone by disturbing its biology and the mechanical behavior associated. This research can be expected to add to our fundamental understanding of how to better (i) treat patients with OA and (ii) diagnose early OA.

Segmentation of bone layers (1 and 2) and vascularization (3) in knee condyles using Nano Ct and Histology using H&E staining